2019
1. Yasuhiro Katahira,# Hiroshi Higuchi,# Hiromichi Matsushita,Takashi Yahata, Yuichiro Yamamoto, Ryo Koike, Kiyoshi Ando,Katsuaki Sato, Ken-Ichi Imadome, and Ai Kotani
Increased Granulopoiesis in the Bone Marrow following Epstein-Barr Virus Infection
Sci Rep. 2019; 9: 13445.
Web




2018

1.Masatoshi Kakizaki, Yuichiro Yamamoto, Suemi Yabuta, Natsumi Kurosaki, Tatehiro Kagawa, Ai Kotani
The immunological function of extracellular vesicles in hepatitis B virus-infected hepatocytes
PLoS ONE 13(12): e0205886
Web

2 .Higuchi H, Yamakawa N, Imadome KI, Yahata T, Kotaki R, Ogata J, Kakizaki M, Fujita K, Lu J,       Yokoyama K, Okuyama K, Sato A, Takamatsu M, Kurosaki N, Alba SM, Azhim A, Horie R, Watanabe T,  Kitamura T, Ando K, Kashiwagi T, Matsui T, Okamoto A, Handa H, Kuroda M, Nakamura N, Kotani A.
   Role of exosomes as a proinflammatory mediator in the development of EBV-associated lymphoma.

   Blood. 2018 Jun 7;131(23):2552-2567.Web

 

2017

1. Kotaki R, Higuchi H, Ogiya D, Katahira Y, Kurosaki N, Yukihira N, Ogata J, Yamamoto H,
    Mohamad Alba S, Azhim A, Kitajima T, Inoue S, Morishita K, Ono K, Koyama-Nasu R, Kotani A.
   Imbalanced expression of polycistronic miRNA in acute myeloid leukemia.
   International Journal of Hematology. 2017;pp1-9. (Springer Japan) LinkIconWeb

2. Kotaki R, Kotani A.
    A single miRNA complements transcription factor deficiency through the TGF pathway at time of
    B-cell lineage determination.
    Rinsho Ketsueki. 2017;58(7):792-797. LinkIconWeb

3. Kotanki R, Nasu-Koyama R, Yamakawa N, and Kotani A. 
    miRNAs in Normal and Malignant Hematopoiesis.  
    International Journal of Molecular Sciences. 2017;18(7). pii: E1495. LinkIconWeb
 
2016
1. Kotani A.
    Roles of Epstein–Barr Virus Micro RNAs in Epstein–Barr Virus-Associated Malignancies.
    Chronic Inflammation Mechanisms and Regulation. 2016;235-45. (Springer Japan) LinkIconWeb
  
2. Kishikawa T, Otsuka M, Yoshikawa T, Ohno M, Yamamoto K, Yamamoto N, Kotani A, Koike K.
    Quantitation of circulating satellite RNAs in pancreatic cancer patients. 
    JCI insight. 2016;1(8). e86646. LinkIconWeb
 
3. Yamamoto H, Lu J, Oba S, Kawamata T, Yoshimi A, Kurosaki N, Yokoyama K, Matsushita H,
    Kurokawa M, Tojo A, Ando K, Morishita K, Katagiri K, Kotani A.
    miR-133 regulates Evi1 expression in AML cells as a potential therapeutic target.
    Scientific Reports. 2016;6:19204. LinkIconWeb
 
4. Sato A, Yamakawa N, Kotani A.
    Pathogenesis and novel therapy for EBV-related B-cell lymphoma.
    Rinsho Ketsueki. 2016;57(1):3-8. LinkIconWeb
 
5. 扇屋大輔, 山本春菜, 幸谷愛
    miRNAによる予後不良白血病の制御
    別冊BIO Clinica Vol.5 No.1 (2016年1月号) CLINICAL TOPICS (北隆館) LinkIconWeb
 
2014
1. Sato A, Yamakawa N, Kotani A.
    The role of tumor-derived secretary small RNAs in EBV related lymphoma.
    Uirusu. 2014;64(1):43-8. LinkIconWeb
 
2. Yamakawa N, Okuyama K, Ogata J, Kanai A, Helwak A, Takamatsu M, Imadome K,
    Takakura K, Chanda B, Kurosaki N, Yamamoto H, Ando K, Matsui H, Inaba T, Kotani A.
    Novel functional small RNAs are selectively loaded onto mammalian Ago1.
    Nucleic Acids Res. 2014;42(8):5289-301. LinkIconWeb
 
3. Kotani A.
    Guest editorial: noncoding RNA in hematopoietic system.
    Int J Hematol. 2014;99(5):529-30. LinkIconWeb
 
4. Okuyama K, Ogata J, Yamakawa N, Chanda B,  Kotani A.
    Small RNA as a regulator of hematopoietic development immune response in infection and
    tumorigenesis.
    Int J Hematol. 2014;99(5):553-60. LinkIconWeb
 
5. Kotani A.
    Genomic mutator Activation-induced cytidine deaminase (AID) as a therapeutic target.
    Rinsho Ketsueki. 2014;55(7):780-4. LinkIconWeb
 
6. 緒方洵, 保科貴宏, 山本春菜, 幸谷愛
    RNA-RAN相互作用の新概念
    実験医学 Vol.32 No.14 (2014年9月号) p.2271-5 (羊土社) LinkIconWeb
 
7. 奥山一生, 幸谷愛
    マイクロRNAによる血液細胞分化制御
    血液内科 Vol.68 No.6 (2014年6月号) p.725-9 (科学評論社) LinkIconWeb
 
2013
1. Okuyama K, Ikawa T, Gentner B, Hozumi K, Harnprasopwat R, Lu J, Yamashita R, Ha D,
    Toyoshima T, Chanda B, Kawamata T, Yokoyama K, Wang S, Ando K, Lodish HF, Tojo A,
    Kawamoto H, Kotani A.
    MicroRNA-126-mediated control of cell fate in B-cell myeloid progenitors as a potential
    alternative to transcriptional factors.
    Proc Natl Acad Sci U S A. 2013;110(33):13410-5. LinkIconWeb
 
2. Yokoyama K, Yokoyama N, Izawa K, Kotani A, Hozumi K, Tojo A.
    In vivo leukemogenic potential of an interleukin-7 receptor α chain mutant in hematopoietic
    stem and progenitor cells.
    Blood. 2013 Dec 19;122(26):4259-63. LinkIconWeb
 
3. 横山和明, 幸谷愛
    血液疾患・免疫疾患におけるエクソソーム
    細胞工学 Vol.32 No.1 (2013年1月号) p.32-7 (学研秀潤社) LinkIconWeb
 
2012
1. Honjo T, Kobayashi M, Begum N, Kotani A, Sabouri S, Nagaoka H.
    The AID Dilemma: Infection, or Cancer?
    Adv Cancer Res. 2012;113:1-44. LinkIconWeb
 
2. Kawamata T, Lu J, Sato T, Tanaka M, Nagaoka H, Agata Y, Toyoshima T, Yokoyama K,
    Oyaizu N, Nakamura N, Ando K, Tojo A, Kotani A.
    Imatinib mesylate directly impairs class switch recombination through down-regulation
    of AID: its potential efficacy as an AID suppressor.
    Blood. 2012;119(13):3123-7. LinkIconWeb
 
3. Lu J, Chanda B, Kotani A.
    Epstein-Barr Virus-Encoded miRNAs in Epstein-Barr Virus-Related Malignancy.
    Hematology - Science and Practice. 2012;409-25. LinkIconWeb
  
 2011
 1. 幸谷愛
    microRNAの異常
    みんなに役立つ悪性リンパ腫の基礎と臨床 改訂版 (2011年2月発行) p.60-5 (医薬ジャーナル社) LinkIconWeb

X

2016
 
EBV establishes the tumor microinvironment by exosome-mediated delivery of miRNA
   to macrophages. (English Oral Presentation)
   Higuchi H, Yamakawa N, Ando K, Kotani A.
   第45回日本免疫学会学術集会 2016/12/5~7 国内
 
single miRNA can rescue B cell development under EVF1 deficiency. (Poster Presentation)
   Kotaki R, Ikawa T, Kometani K, Kurosaki T, Hozumi K, Kawamoto H, Kotani A.
   第45回日本免疫学会学術集会 2016/12/5~7 国内
  
転写因子欠損化におけるmiRNAによる細胞運命制御 (招待講演)
   幸谷愛
   第39回日本分子生物学会年会 2016/11/30~12/2 国内
 
EBV Establishes the Tumor Microenvironment by Exosome-mediated Delivery of miRNA
   to Macrophages. (Invited Speaker)
   Kotani A.
   The 57th Autumn Meeting of the Korean Society of Hematology 2016/11/11~12
   Daejeon, Korea 国外
 
A single miRNAs rescue transcriptional factor deficiency in B cell lineage specification though TGF
   beta pathway. (招待講演)
   Kotani A.
   第78回日本血液学会学術集会 2016/10/13~15 国内
 
Analysis of the essential role of macrophages in EBV-related lymphoma using humanized mice.
   (口頭発表)
   Higuchi H, Yamakawa N, Kotani A.
   第78回日本血液学会学術集会 2016/10/13~15 国内
 
miR-133 regulates Evi1 expression in AML cells as a potential therapeutic target. (口頭発表)
   Yukihira N, Ogiya D, Yamamoto H, Kurokawa M ,Ando K, Morishita K, Kotani A.
   第78回日本血液学会学術集会 2016/10/13~15 国内
 
A case of Hodgkin lymphoma complicated by bilateral anterior subcapsular cataracts.
   (ポスター発表)
   Ogiya D, Kojima M, Ohmachi K, Ogawa Y, Kawada H, Ando K, Kotani A.
   第78回日本血液学会学術集会 2016/10/13~15 国内
 
三次元培養化におけるホジキンリンパ腫細胞の遊走 (口頭発表)
   保科貴広, 幸谷愛, 北村俊雄
   第78回日本血液学会学術集会 2016/10/13~15 国内
 
EBV establishes the tumor microenvironment by exosome-mediated delivery of miRNA
   to macrophages. (招待講演)
   Kotani A.
   第75回日本癌学会学術総会 2016/10/6~8 国内
 
A single miRNA rescues EBF1 deficiency in B cell development partly through TGF-β pathway.
   (English Oral Presentation)
   Kotaki R, Miyazono K, Kotani A.
   第75回日本癌学会学術総会 2016/10/6~8 国内
 
Analysis of the Essential Role of Macrophages in the Inflammatory Niche of EBV-associated
   Lymphoma. (ポスター発表)
   Higuchi H, Kotani A.
   第75回日本癌学会学術総会 2016/10/6~8 国内
 
・転写因子欠損を補完するmiRNAによる造血運命決定機構と白血病の新しい理解 (招待講演)
   幸谷愛
   第89回日本生化学会大会 2016/9/25~27 国内
 
EBV establishes the tumor microenvironment by exosome-mediated delivery of miRNA
   to macrophages(招待講演)
   Kotani A.
   第8回日本RNAi研究会 2016/8/31~9/2 国内 
 
miR-195は転写因子EBF1の欠損による B 細胞分化能の欠失を補完できる (口演発表)
   上滝隆太郎, 幸谷愛
   第8回日本RNAi研究会 2016/8/31~9/2 国内
 
エクソソームを介したEBV由来miRNAのマクロファージへの輸送がEBV陽性リンパ腫を引き起こす
   (ポスター発表)
   樋口廣士, 幸谷愛
   第8回日本RNAi研究会 2016/8/31~9/2 国内
 
アポトーシス細胞におけるRNA分解機構の解析 (ポスター発表)
   緒方洵, 幸谷愛
   第8回日本RNAi研究会 2016/8/31~9/2 国内
 
EBV establishes the tumor microenvironment by exosome-mediated delivery of miRNA 
   to macrophages. (Poster Presentation) 
   Kotani A. 
   Keystone Symposia : Exosomes/Microvesicles: Novel Mechanisms of Cell-Cell Communication (E4)
   2016/6/17~6/22 Keystone, USA 国外
 
EBV infected B cells deliver exosome essential to lymphoma development and maintenance. 
   (Poster Presentation) 
   Kotani A. 
   Keystone Symposia : B Cells at the Intersection of Innate and Adaptive Immunity (E3)
   2016/5/29~6/2 Stockholm, Sweden 国外
 
Functional and comprehensive investigation of microRNA targeting Notch receptors. (ポスター発表)
   Nasu R, Okuyama K, Ohgiya D, Hozumi K, Murata A, Ando K, Kotani A.
   第14回幹細胞シンポジウム 2016/5/20~5/21 国内
 
A single miRNA rescues EBF1 deficiency in B cell development though TGF- β pathway.
   (ポスター発表)
   Kotaki R, Kotani A.
   第14回幹細胞シンポジウム 2016/5/20~5/21 国内
 
EBV establishes the tumor microenvironment by exosome-mediated delivery of miRNA
   to macrophages. (Invited Speaker) 
   Kotani A. 
   2nd Bio-iST Symposium 20162016/5/14 Kuala Lumpur, Malaysia 国外
 
Macrophage Depletion Induces the Elimination of EBV+ Cells In Vivo. (Poster Presentation)
   Higuchi H, Kotani A.
   The 7th JSH International Symposium 2016. 2016/5/13~5/14 国内
 
EBV establishes the tumor microenvironment by exosome-mediated delivery of miRNA
   to macrophages. (Poster Presentation)
   Yamakawa N, Kotani A.
   Cold Spring Harbor Laboratory : Gene Expression & Signaling in the Immune System.
   2016/4/26~4/30 Cold Spring Harbor, USA 国外